PHP2Shell gave many research teams a crash course in how much they really know about the tools holding their study data. Here are the ten questions worth asking before your next study goes live, and what a good answer sounds like. The PHP2Shell vulnerabilities forced organisations across Europe to check, in a hurry, which of their systems were exposed. Some

Last week, the PHP project released emergency fixes for PHP2Shell, two critical flaws that let attackers take control of an unpatched web server without logging in. In the days since, the reaction across clinical research has followed two very different patterns. Teams running software on their own servers have spent the week finding out which applications use PHP, who installed

For many years, operational planning was seen as something that happened once a clinical trial protocol had been finalised. Teams would complete the protocol, obtain approvals and then begin thinking about site activation, documentation, study management and patient recruitment. Today, that approach is changing. As clinical research becomes increasingly complex, clinical trial operational planning is starting much earlier. Sponsors, CROs

Cambiar un protocolo en un ensayo clínico es una situación mucho más habitual de lo que puede parecer. La aparición de nuevos datos, la evolución del reclutamiento, las recomendaciones de los organismos reguladores o la necesidad de mejorar la seguridad de los pacientes hacen que las modificaciones formen parte del desarrollo natural de muchos estudios. El problema no es que